A case of disappearing amyloid on technetium pyrophosphate scan

We present a patient with ATTR cardiac amyloidosis who had a strongly positive initial Tc-PYP scan, with a dramatic decrease in Tc-PYP uptake on repeat scan after 3 years of tafamidis treatment. However, myocardial biopsy showed persistent diffuse amyloid deposits. This case highlights the need for further studies regarding the utility of serial Tc-PYP scans in monitoring the progress of ATTR cardiomyopathy.

http://link.springer.com/10.1007/s12350-023-03316-1

Source: Journal of Nuclear Cardiology - June 20, 2023 Category: Nuclear Medicine Source Type: research