A positive feedback cycle between the alarmin S100A8/A9 and NLRP3 inflammasome-GSDMD signalling reinforces the innate immune response in Candida albicans keratitis

ConclusionsThe present study is the first to reveal the critical roles of the alarmin S100A8/A9 in the immunopathology ofCandida albicans keratitis, highlighting a promising approach for therapeutic intervention in the future.

Source: Inflammation Research - June 19, 2023 Category: Research Source Type: research