Ovaries out of control – hormonal strategies

The perimenopausal transition represents a therapeutic challenge for clinicians as the follicular activity of the ovaries does not decline gradually and evenly, but is accompanied by a pronounced up and down of hormone production. The female menstrual cycle involves a highly regulated chain of neuro-endocrine phenomena, maintained by a constant dialogue between the hypothalamus, the pituitary gland and the ovaries. Besides FSH, LH, estradiol and progesterone, other components of this dialogue are inhibin A and B, AMH as well as the KNDy neurons in the arcuate nucleus.
Source: Maturitas - Category: Primary Care Authors: Tags: Abstract ID: 144 Source Type: research