B cells: The many facets of B cells in allergic diseases

B cells play a key role in our immune system through their ability to produce antibodies, suppress a pro-inflammatory state, and contribute to central immune tolerance. We aim to provide an in-depth knowledge of the molecular biology of B cells, including their origin, developmental process, types and subsets, and functions. In allergic diseases, B cells are well-known to induce and maintain immune tolerance through the production of suppressor cytokines such as interleukin-10 (IL-10). Similarly, B cells protect against viral infections such as SARS-CoV-2 that caused the recent COVID-19 pandemic.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research