The BET PROTAC inhibitor dBET6 protects against retinal degeneration and inhibits the cGAS-STING in response to light damage

Chronic inflammation significantly contributes to photoreceptor death in blinding retinal diseases such as age-related macular degeneration (AMD) and retinitis pigmentosa (RP). Bromodomain and extraterminal do...

Source: Journal of Neuroinflammation - May 22, 2023 Category: Neurology Authors: Xingfei Zhu, Wei Liu, Xiangcheng Tang, Yulin Chen, Xiangyu Ge, Qin Ke, Xingmiao Liang, Yuwen Gan, Yingfeng Zheng, Ming Zou, Mi Deng, Yizhi Liu, David Wan-Cheng Li and Lili Gong Tags: Research Source Type: research