MET Inhibits the Proliferation of EC Cells by Increasing MPA Sensitivity

CONCLUSIONS: MET inhibited the proliferation of EC cells by increasing MPA-sensitivity, which was dependent on the inhibition of the CD133 expression and the Akt/mTOR pathway. In addition, if MET acts as an effective progestin sensitizer, it certainly offers promising therapeutic prospects for patients with early-stage EC or overgrown endometrium who have fertility requirements.PMID:37171945
Source: Alternative Therapies in Health and Medicine - Category: Complementary Medicine Authors: Source Type: research