Metabolic-Related Index to Predict Post-Transplantation Diabetes Mellitus After Kidney Transplantation
This article aims to explore the convenient and inexpensive
values of metabolic-related markers, including TyG, TyG-BMI, TG/HDL-C,
and non-HDL-C/HDL-C for predicting PTDM. The data of 191 kidney
transplant recipients in our center were collected retrospectively. The
association between TyG, TyG-BMI, TG/HDL-C, non-HDL-C/HDL-C and
the risk of PTDM was examined by the area under the curve and logistic
regression analyses. During 6 months follow-up, 12.04% of KT recipients
developed PTDM, and significantly higher values of TyG-BMI, TyG, and
non-HDL-C/HDL-C was found in patients with PTDM than in nondiabetic
patients, especially among the recipients taking tacrolimus, regardless of
gender. The incidence of PTDM increased along with the values of TyG or TyG-BMI.
After adjusting for multiple potential factors, recipients with the highest
trisector of TyG or TyG-BMI still had a higher risk of PTDM morbidity. In
conclusion, TyG, TyG-BMI, TG/HDL-C and non-HDL-C/HDL-C can be
used as cost-effective and promising monitors to identify individuals at high
risk of PTDM, and TyG-BMI was the best alternative marker among the four
markers. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text
Source: Hormone and Metabolic Research - Category: Endocrinology Authors: Xiaojie, Ni Bicheng, Chen Yongling, Li Tingting, Huang Yi, Zhou Chen, Zimiao Tags: Original Article: Endocrine Care Source Type: research
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