Haemophilus parainfluenzae aortic prosthetic valve endocarditis (PVE) successfully treated with oral levofloxacin

Antibiotic treatment of native valve infective endocarditis (IE) traditionally consists of 4–6 weeks of intravenous (IV) antibiotic therapy. Oral (PO) antibiotic therapy is being used more frequently, for part or all of treatment for IE but experience in treating IE with PO antibiotics is limited. Preferable agents for oral therapy of IE are antibiotics with a high degree of activity against the IE pathogen and that have high bioavailability (>90%) so that achievable serum and tissue levels are the same as with equivalent IV antibiotics.

Source: Heart and Lung - May 18, 2015 Category: Intensive Care Authors: Burke A. Cunha, Kunal Brahmbhatt, Muhammad Raza Source Type: research