Organotin mixtures reveal interactions that modulate adipogenic differentiation in 3T3-L1 preadipocytes

In conclusion, DBT and TPT interfere with TBT's adipogenic differentiation possibly via PPARγ signaling. These findings highlight the antagonistic effects among organotins and the need to understand the effects and mechanism of action of complex organotin mixtures on adipogenic outcomes.PMID:37142754 | DOI:10.1007/s00204-023-03512-5

Source: Archives of Toxicology - May 4, 2023 Category: Toxicology Authors: Elvis Ticiani Yong Pu Madison White Victoria Adomshick Almudena Veiga-Lopez Source Type: research