Management of portal hypertension, Budd – Chiari syndrome and portal vein thrombosis

Portal hypertension is associated with many of the known complications of cirrhosis and has an enormous impact on prognosis. Ascites and hepatic encephalopathy represent the most common complications of cirrhosis; both are associated with a significantly worse prognosis, with 50% survival over 1 –2 years. Acute variceal bleeding remains a life-threatening complication and leading cause of death in individuals with cirrhosis. Advances in variceal bleeding management, including empirical antibiotic use, vasoactive drugs, early endoscopy and therapies such as transjugular intrahepatic portos ystemic shunts (TIPS), have resulted in improved mortality rates, currently 11–20% per episode.
Source: Medicine - Category: Internal Medicine Authors: Tags: Management problems in liver disease Source Type: research