Exercise Changes Gut Microbiota: A New Idea to Explain that Exercise Improves Autism
Int J Sports Med DOI: 10.1055/a-2018-2477The effect of exercise interventions on autism spectrum disorder (ASD) has been
demonstrated in many studies, and the discovery of a bidirectional relationship
between the gut microbiome (GM) and the central nervous system (CNS) has led to
the concept of the microbial gut-brain axis (MGBA) and has linked the abnormal
GM to a variety of neuropsychiatric disorders, autism being one of them.
Research on improving the GM through exercise is also starting to come into
focus. However, there are currently few studies on exercise intervention in the
GM of autism. The purpose of this review was to find evidence to explore the
possible potential effects of exercise to improve the behavior of individuals
with autism in the MGBA in this treatment, as well as the potential of GM as an
exercise treatment for autism. We will explore (1) changes in GM components of
ASD and their relationship to the pathophysiology of ASD; (2) the relationship
between exercise and changes in GM components, and (3) the effect of exercise on
GM in CNS disorders. Ultimately, we concluded that Streptococcus,
Bifidobacterium, Clostridium, Bacteroides, and
Blautia may be potential effectors through the MGBA network during
exercise to ameliorate ASD targeting microbiotas. They deserve high attention in
th...
Source: International Journal of Sports Medicine - Category: Sports Medicine Authors: Xue, Yaqi An, Shasha Qiu, Weihua Zhang, Weinan Fu, Limin Zhen, Zhiping Tags: Review Source Type: research