Metabolic Syndrome and Periodontal Disease

AbstractPurpose of ReviewMetabolic syndrome is a systemic condition that has components such as obesity, dyslipidemia, hyperglycemia, and hypertension and is associated with an increased risk of cardiovascular disease and type 2 diabetes. Periodontitis is a chronic inflammatory disease characterized by progressive attachment loss that develops as a result of the host response to the dysbiotic plaque microbiome. Periodontal diseases can jeopardize systemic health through various mechanisms as well as be detrimental to oral health. The interlinks of these mechanisms and the pathogenesis of metabolic syndrome cause a bidirectional interaction between the two diseases. This review aimed to evaluate studies focusing on potential interaction mechanisms between periodontal disease and metabolic syndrome and present the clinical implications of these interactions.Recent FindingsStudies dealing with the relationship between metabolic syndrome and components of metabolic syndrome and periodontal disease are available in the literature, and it is reported that the two conditions are generally related. According to literature findings, inflammation is a common pathway in metabolic syndrome and periodontal disease. While both diseases can exacerbate the inflammation and affect the other, it is also seen that the severity of the disease increases by being affected by the increasing chronic inflammation itself. The fact that they have common risk factors other than the intersecting pathways...
Source: Current Oral Health Reports - Category: Dentistry Source Type: research