Sex Differences in Cocaine Sensitization Vary by Mouse Strain

Conclusions: While sex differences in drug addiction may be observed, these effects can be mitigated, or even reversed, dependent on genetic background. The clinical implications being that absent of understanding the genetic variables underlying vulnerability to addiction, sex provides little information regarding the predisposition of an individual to drug abuse.
Source: Neuroendocrinology - Category: Endocrinology Source Type: research