Combination Moderate-Intensity Statin  and Ezetimibe Therapy for Elderly Patients With Atherosclerosis

CONCLUSIONS: Moderate-intensity statin with ezetimibe combination therapy showed similar cardiovascular benefits to those of high-intensity statin monotherapy with lower intolerance-related drug discontinuation or dose reduction in elderly patients with ASCVD having a higher risk of intolerance, nonadherence, and discontinuation with high-intensity statin therapy. (RAndomized Comparison of Efficacy and Safety of Lipid-lowerING With Statin Monotherapy Versus Statin/Ezetimibe Combination for High-risk Cardiovascular Diseases [RACING Trial]; NCT03044665).PMID:37019580 | DOI:10.1016/j.jacc.2023.02.007

Source: Atherosclerosis - April 5, 2023 Category: Cardiology Authors: Sang-Hyup Lee Yong-Joon Lee Jung Ho Heo Seung-Ho Hur Hyun Hee Choi Kyung-Jin Kim Ju Han Kim Keun-Ho Park Jung Hee Lee Yu Jeong Choi Seung-Jun Lee Sung-Jin Hong Chul-Min Ahn Byeong-Keuk Kim Young-Guk Ko Donghoon Choi Myeong-Ki Hong Yangsoo Jang Jung-Sun Ki Source Type: research