Resveratrol-induced SIRT1 activation inhibits glycolysis-fueled angiogenesis under rheumatoid arthritis conditions independent of HIF-1 α

ConclusionGlycolysis provides additional energy to sustain Rho/ROCK activation in RA subjects, which promotes VEGF-driven angiogenesis and can be inhibited by SIRT1 activation.

http://link.springer.com/10.1007/s00011-023-01728-w

Source: Inflammation Research - April 4, 2023 Category: Research Source Type: research