A 7-day decitabine included conditioning regimen accelerated donor hematopoietic engraftment while reduced the occurrence of mucositis without interfering with prognosis

This study was to retrospectively evaluate a 7-day decitabine included regimen with reduced dose of idarubicin for patients with hematologic malignancies who underwent allo-HSCT. Results: A total of 84 patients were enrolled, including 24 cases in 7-day and 60 cases in 5-day decitabine groups, respectively. Patients conditioned with 7-day decitabine regimen showed accelerated neutrophil (12.05 ±1.97 versus 13.86±3.15; u = 9.309, P
Source: Chemotherapy - Category: Cancer & Oncology Source Type: research