Analysis of Fatty Acid composition and Sensitivity to Dietary n-3 PUFA Intervention of Mouse n-3 PUFA-Enriched Tissues/Organs

It is well known that fatty acids, as an important component of the plasma membrane, are involved in modulating cell function and fate. Docosahexaenoic acid (DHA; C22:6 n3) and eicosapentaenoic acid (EPA; C20:5 n3) are the major n-3 polyunsaturated fatty acids (PUFAs), and their function has received a lot of attention [1]. The brain has an abundance of DHA and arachidonic acid (AA; C20:4 n6) selectively esterified into the sn-2 position of phospholipids, as well as low levels of other PUFAs, such as linoleic acid (LA; C18:2 n6), α-linolenic acid (ALA; C18:3 n3), and EPA [2,3].

Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - March 22, 2023 Category: Biomedical Science Authors: Hui Zhang, Yannan He, Chunyan Song, Zhenglong Chai, Chundi Liu, Shuben Sun, Qiuhan Huang, Canxia He, Xiaohong Zhang, Yuping Zhou, Feng Zhao Tags: Original research article Source Type: research