Assessment of the Risk Evaluation and Mitigation Strategy (REMS) for Phentermine-Topiramate to Prevent Exposure During Pregnancy

CONCLUSION: Prenatal exposure seemed to be significantly lower among phentermine-topiramate users under the REMS. Pregnancy testing and contraceptive use appeared to be inadequate for all groups, which deserves attention to prevent the remaining potential exposures.PRIMARY FUNDING SOURCE: None.PMID:36940443 | DOI:10.7326/M22-1743

Source: Annals of Internal Medicine - March 20, 2023 Category: Internal Medicine Authors: Amir Sarayani William Troy Donahoo Christian Hampp Joshua D Brown Almut G Winterstein Source Type: research