Analysis of BRCA1 and BRCA2 alternative splicing in predisposition to ovarian cancer

CONCLUSIONS: This observation indicates that the upregulation of selected naturally occurring transcripts can be stimulated by non-genetic mechanisms and be a potential systemic response to disease progression and/or treatment. However, this hypothesis requires further examination.PMID:36791903 | DOI:10.1016/j.yexmp.2023.104856

Source: Experimental and Molecular Pathology - February 15, 2023 Category: Pathology Authors: Anna Jasiak Magdalena Koczkowska Maciej Stukan Dariusz Wydra Wojciech Biernat Ewa Izycka-Swieszewska Kamil Buczkowski Michael R Eccles Logan Walker Bartosz Wasag Magdalena Ratajska Source Type: research