Endobiliary Radiofrequency Ablation for Malignant Biliary Obstruction over 32-Month Follow-Up

In this report, we present the case of a 58-year-old woman with a history of unresectable hilar cholangiocarcinoma. Initially she was treated with intraductal dilatation of malignancy and placement of a plastic stent and chemotherapy (Gemcitabin ® and Platinol®). Two years later she underwent a second-line chemotherapy with Gemcitabin® and Oxyplatin® because of tumor progression. Despite a second line chemotherapy and placement of an uncovered self-expandible metal stent (ucSEMS) that was extended later on by stent-in stent technique, t here was tumor progression which led to a complex course with relapsing obstructive cholangiosepsis and cholestasis. Because of tumor ingrowth, endobiliary radiofrequency ablation of the malignant stenosis was performed in repeated sessions. This case illustrates that radiofrequency ablation of soli tary malignant biliary obstruction is feasible, safe and allows an improvement of quality of life in non-operable patients.Gastrointest Tumors 2022;9:12 –18
Source: Gastrointestinal Tumors - Category: Gastroenterology Source Type: research