Technology and Type 1 Diabetes: Closed-Loop Therapies

Abstract The concept of a closed-loop, automated insulin delivery system, with continuous glucose sensing and insulin delivery informed by a control algorithm without patient intervention, offers the potential to decrease the burden of diabetes management and modify the significant glycemic excursions associated with conventional therapy. Closed-loop technology represents a change in the treatment paradigm for diabetes as the transition is made from primarily self-management behaviors to automated insulin therapy, potentially relieving the burden and guilt of suboptimal glucose control. The advances in this field have been rapid, and clinical trials are currently underway worldwide testing several systems in various stages of development. We have moved rapidly from inpatient research centers to supervised outpatient settings such as diabetes camps, hotels, and now to the home environment with and without remote monitoring. Recent studies and the potential impact on the care of children with type 1 diabetes are presented in this report.
Source: Current Pediatrics Reports - Category: Pediatrics Source Type: research