Clinical relevance of PD-1 positive CD8 T-cells in gastric cancer

ConclusionThis is one of the largest GC cohorts of mIHC combined with analysis of multiple datasets providing orthogonal validation of the clinical relevance of PD-1+CD8+ T-cells being associated with improved OS. CD8PD-1high tumors have distinct features of an immunologically active, T-cell inflamed TME.

Source: Gastric Cancer - February 12, 2023 Category: Gastroenterology Source Type: research