Contraction of human brain vascular pericytes in response to islet amyloid polypeptide is reversed by pramlintide

The islet amyloid polypeptide (IAPP), a pancreas-produced peptide, has beneficial functions in its monomeric form. However, IAPP aggregates, related to type 2 diabetes mellitus (T2DM), are toxic not only for t...

Source: Molecular Brain - February 15, 2023 Category: Neuroscience Authors: Cristina Nu ñez-Diaz, Dovilė Pocevičiūtė, Nina Schultz, Charlotte Welinder, Karl Swärd and Malin Wennström Tags: Research Source Type: research