Behavioral Improvements Following Lesion Resection for Pediatric Epilepsy: Pediatric Psychosurgery?

Conclusion: We identified five patients with severe behavioral disorders in the setting of lesional epileps y, all of whom demonstrated improvement after surgery. The degree of behavioral abnormality was disproportionate to epilepsy severity, suggesting a more complicated mechanism by which lesional epilepsy impacts behavior. We propose a novel paradigm in which lesionectomy may offer behavioral benefit e ven when seizures are not refractory. Thus, behavioral improvement may be an important novel goal for neurosurgical resection in children with epileptic brain lesions.
Source: Pediatric Neurosurgery - Category: Neurosurgery Source Type: research