Unexpected appearance of KMT2A::MLLT10 fusion transcript in acute myeloid leukemia with t(5;11)(q31;q23.3)
We report here a 65-year-old woman with AML M5b. G-banding and spectral karyotyping demonstrated 46,XX,t(5;11)(q31;q23.3). Fluorescence in situ hybridization revealed not only separated 5 ’ and 3’ KMT2A signals but a faint 5’ KMT2A signal.
Source: Cancer Genetics and Cytogenetics - Category: Genetics & Stem Cells Authors: Katsuya Yamamoto, Hisayuki Matsumoto, Sakuya Matsumoto, Rina Sakai, Akihito Kitao, Marika Watanabe, Hideaki Goto, Takeshi Sugimoto, Yoshihiko Yano, Kimikazu Yakushijin, Hironobu Minami Tags: Case Report Source Type: research
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