Intramural Papers of the Month

<img width="100" src="https://factor.niehs.nih.gov/sites/niehs-factor/files/styles/large/public/thumb825983.jpg?itok=otjNGPEU" /><br /><p>National Toxicology Program (NTP) researchers and collaborators evaluated the usefulness of quantitative high-throughput approaches to assess the genotoxicity, or the ability to cause DNA damage, of compounds in the Tox21 library of 10,000 compounds. To do this, they assessed p53 activity in human colon cancer cells (HCT-116). p53 is a transcription factor that is activated in response to cellular stress, particularly DNA damage.</p> (read more)
Source: Environmental Factor - NIEHS Newsletter - Category: Environmental Health Source Type: news