Phytochemical profile and anti-inflammatory activity of a commercially available Rhodiola rosea root extract

This study was aimed at providing a detailed phytochemical characterization of the Rhodiola 5%, a commercially available extract of R. rosea roots, and resulted in the characterization of 18 secondary metabolites, including 13 polyphenols and 6 terpenoids, and in the discovery of the new rhodiosidin (5), the first R. rosea metabolite to show both terpenoid and cinnamoyl moieties. The 5-lipoxygenase inhibiting activity of the main components was characterized and disclosed that rosiridin (6), kenposide A and rosavins are mainly responsible for this activity of the extract.PMID:36716798 | DOI:10.1016/j.fitote.2023.105439

Source: Fitoterapia - January 30, 2023 Category: Biochemistry Authors: Francesca Masi Giuseppina Chianese Robert K Hofstetter Arianna Lucia Cavallaro Antonella Riva Oliver Werz Orazio Taglialatela-Scafati Source Type: research