Permethrin steal effect by unmasked corneocytic keratin in topical therapy of scabies

Conclusion: The results provide further evidence for a relevant pharmacokinetic influencing factor in the epicutaneous application of permethrin and a rationale for the necessity of keratolytic pretreatment in hyperkeratotic skin for the effective use of topical permethrin application in scabies.
Source: Skin Pharmacology and Physiology - Category: Dermatology Source Type: research