G-protein coupled estrogen receptor (GPER1) activation promotes synaptic insertion of AMPA receptors and induction of chemical LTP at hippocampal temporoammonic-CA1 synapses

It is well documented that 17 β estradiol (E2) regulates excitatory synaptic transmission at hippocampal Shaffer-collateral (SC)-CA1 synapses, via activation of the classical estrogen receptors (ERα and ERβ). H...

Source: Molecular Brain - January 28, 2023 Category: Neuroscience Authors: Leigh Clements, Amy Alexander, Kirsty Hamilton, Andrew Irving and Jenni Harvey Tags: Research Source Type: research