Molecules, Vol. 28, Pages 1242: Advances in the Study of Probiotics for Immunomodulation and Intervention in Food Allergy

Molecules, Vol. 28, Pages 1242: Advances in the Study of Probiotics for Immunomodulation and Intervention in Food Allergy Molecules doi: 10.3390/molecules28031242 Authors: Yan-yan Huang Yan-tong Liang Jia-min Wu Wei-tong Wu Xin-tong Liu Ting-ting Ye Xiao-rong Chen Xin-An Zeng Muhammad Faisal Manzoor Lang-hong Wang Food allergies are a serious food safety and public health issue. Soybean, dairy, aquatic, poultry, and nut products are common allergens inducing allergic reactions and adverse symptoms such as atopic dermatitis, allergic eczema, allergic asthma, and allergic rhinitis. Probiotics are assumed as an essential ingredient in maintaining intestinal microorganisms’ composition. They have unique physiological roles and therapeutic effects in maintaining the mucosal barrier, immune function, and gastrointestinal tract, inhibiting the invasion of pathogenic bacteria, and preventing diarrhea and food allergies. Multiple pieces of evidence reveal a significant disruptive effect of probiotics on food allergy pathology and progression mechanisms. Thus, this review describes the allergenic proteins as an entry point and briefly describes the application of probiotics in allergenic foods. Then, the role of probiotics in preventing and curing allergic diseases by regulating human immunity through intestinal flora and intestinal barrier, modulating host immune active cells, and improving host amino acid metabolism are described in detail. The...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research