Pentoxifylline and tocopherol for the treatment of osteoradionecrosis of the jaws. A systematic review

CONCLUSIONS: PENTO treatment achieved a complete disease control in a significant number of patients in all studies. However, there is no standardized protocol for administering the therapy. It is necessary to determine the pharmacological doses and to evaluate the benefits of adding antibiotics and clodronate. Good quality clinical trials are needed to develop a successful algorithm for the management of ORN of the jaws.PMID:36641743 | DOI:10.4317/medoral.25729
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - Category: ENT & OMF Authors: Source Type: research