Clinical sequencing identifies potential actionable alterations in a high rate of urachal and primary bladder adenocarcinomas

ConclusionsIn this study, we developed a data-processing pipeline for the detection and therapeutic interpretation of genetic alterations in two rare cancers. Our analyses revealed actionable mutations in a high rate of cases, suggesting that this approach is a potentially feasible strategy for both UrC and PBAC treatments.

Source: Cancer Medicine - January 21, 2023 Category: Cancer & Oncology Authors: Melinda Varadi, Nikolett Nagy, Henning Reis, Boris Hadaschik, Christian Niedworok, Orsolya Modos, Attila Szendroi, Jason Ablat, Peter C. Black, David Keresztes, Anita Csizmarik, Csilla Olah, Nadine T. Gaisa, Andras Kiss, Jozsef Timar, Erika Tags: RESEARCH ARTICLE Source Type: research