Targeting TRMT5 suppresses hepatocellular carcinoma progression via inhibiting the HIF-1 α pathways

In conclusion, our study revealed that targetingTRMT5 could inhibit HCC progression and increase the susceptibility of tumor cells to chemotherapy drugs. Thus,TRMT5 might be a carcinogenesis candidate gene that could serve as a potential target for HCC therapy.

Source: Journal of Zhejiang University. Science. B. - January 1, 2023 Category: Universities & Medical Training Source Type: research