Alterations of spontaneous cortical and subcortical activity in type 2 diabetes mellitus with and without depression

Conclusions: The abnormalities of spontaneous cortical activity in PCC and subcortical activity in the hippocampus might represent the neurobiological feature of cerebral dysfunction in T2DM. Notably, the altered subcortical activity in the right putamen might mainly associate with negative emotion in T2DM, which could be a promising biomarker for recognizing early cerebral dysfunction in depressed T2DM.
Source: Neuroendocrinology - Category: Endocrinology Source Type: research