Gefapixant, a Novel P2X3 Antagonist, Protects against Post Myocardial Infarction Cardiac Dysfunction and Remodeling Via Suppressing NLRP3 Inflammasome

ConclusionIt is suggested that P2X3 inhibition by gefapixant ameliorates post-infarct autonomic nervous imbalance, cardiac dysfunction, and remodeling possibly via inactivating NLRP3 inflammasome.

http://link.springer.com/10.1007/s11596-022-2658-5

Source: Journal of Huazhong University of Science and Technology -- Medical Sciences -- - January 9, 2023 Category: Research Source Type: research

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