Randomized control trial of prednisolone and doxycycline in patients with acute interstitial nephritis of unknown aetiology

ConclusionPrednisolone and doxycycline were not beneficial for the earliest presentation of CKDu at 6  months. However, there is a potential benefit of prednisolone on the long-term outcome of CKDu. An adequately powered steroid trial using patients reaching <  30 ml/min/1.73m2 eGFR by 3  years, as an outcome is warranted for AIN of unknown aetiology.Trial registrationSri Lanka Clinical Trial Registry SLCTR/2014/007, Registered on the 31st of March 2014.
Source: Trials - Category: Research Source Type: clinical trials