TSAb Modulates Microglia M1 Polarization via Activation of the TSHR-Mediated NF- κB Signaling Pathway

Conclusions: TSAb can induce abnormal activation of microglia, polarize to the M1 phenotype, and promote the inflammatory cascade reaction, in which TSHR plays a key role in NF- κB activation and proinflammatory cytokine release.
Source: Neuroendocrinology - Category: Endocrinology Source Type: research