Can low dose of intratracheal dexmedetomidine be used to attenuate peri-extubation cough ? - A prospective, double-blinded, randomized clinical trial

Conclusion: We conclude that both 0.3 mic/kg and 0.5 mic/kg of dexmedetomidine when given intratracheally are effective in preventing peri-extubation cough. Further, 0.3 mic/kg dexmedetomidine showed a better recovery profile compared to 0.5 mic/kg dexmedetomidine when administered intratracheally.
Source: Saudi Journal of Anaesthesia - Category: Anesthesiology Authors: Source Type: research