Neuroaxonal and Glial Markers in Patients of the Same Age With Multiple Sclerosis

Discussion In our cohort of patients of the same age, we report consistent correlations of sNfL and sGFAP with a range of metrics, especially in progressive MS, whereas contactin-1 was not related to clinical or MRI measures. This demonstrates the potential of sNfL and sGFAP as complementary biomarkers of neurodegeneration, reflected by disability, in progressive MS.

http://nn.neurology.org/cgi/content/short/10/2/e200078?rss=1

Source: Neurology Neuroimmunology and Neuroinflammation - December 21, 2022 Category: Neurology Authors: Loonstra, F. C., de Ruiter, L. R. J., Koel-Simmelink, M. J. A., Schoonheim, M. M., Strijbis, E. M. M., Moraal, B., Barkhof, F., Uitdehaag, B. M. J., Teunissen, C., Killestein, J. Tags: Research Article Source Type: research