Molecules, Vol. 28, Pages 25: Discovery of Hepatotoxic Equivalent Markers and Mechanism of Polygonum multiflorum Thunb. by Metabolomics Coupled with Molecular Docking

This study not only found that the HEMs of PMT were TSG and EG, but also clarified that PMT might affect purine metabolism to induce liver injury, which contributed to our understanding of the underlying mechanisms of PMT hepatotoxicity.

Source: Molecules - December 21, 2022 Category: Chemistry Authors: Yinhuan Zhang Lirong Liu Menghan Feng Hao Wu Yihang Dai Zhixin Jia Cong Fang Mingyan Liu Xiaoning Yan Meixia Zhu Beibei Huang Biqiong Qu Hongbin Xiao Tags: Article Source Type: research