Short-term pulmonary and systemic effects of hydrocortisone initiated 7-14 days after birth in ventilated very preterm infants: a secondary analysis of a randomised controlled trial

Conclusions Systemic hydrocortisone initiated between 7 and 14 days after birth in ventilated preterm infants improves pulmonary condition, thereby facilitating weaning and extubation from invasive ventilation. The effects of hydrocortisone on blood glucose levels and blood pressure were mild and of limited clinical relevance. Trial registration number Netherlands Trial Register (NTR2768; https://www.trialregister.nl/trial/2640) and European Union Clinical Trials Register (EudraCT, 2010-023777-19).

http://fn.bmj.com/cgi/content/short/108/1/20?rss=1

Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - December 15, 2022 Category: Perinatology & Neonatology Authors: Halbmeijer, N. M., Onland, W., Cools, F., Kroon, A., van der Heide-Jalving, M., Dijk, P., van Straaten, H. L. M., te Pas, A. B., Mohns, T., Bruneel, E., van Heijst, A. F. J., Kramer, B., Debeer, A., Zonnenberg, I. A., Marechal, Y., Blom, H., Plaskie, K., Tags: Original research Source Type: research