Levetiracetam versus fosphenytoin as a second-line treatment after diazepam for adult convulsive status epilepticus: a multicentre non-inferiority randomised control trial

Conclusion
The efficacy of LEV was similar to that of FPHT for adult SE following the administration of diazepam. LEV may be recommended as a second-line treatment for SE along with phenytoin/FPHT.

Trial registration number
jRCTs031190160.

Source: Journal of Neurology, Neurosurgery and Psychiatry - December 14, 2022 Category: Neurosurgery Authors: Nakamura, K., Marushima, A., Takahashi, Y., Mochizuki, M., Kimura, A., Fukuda, Y., Asami, M., Nakamoto, H., Egawa, S., Kaneko, J., Unemoto, K., Kondo, Y., Yonekawa, C., Uchida, M., Hoshiyama, E., Yamada, T., Maruo, K., Ishikawa, E., Matsumaru, Y., Inoue, Tags: Open access Epilepsy Source Type: research