Resolved Severe Primary Hypothyroidism in Sensenbrenner Syndrome Post Hepatorenal Transplantation: A Case Report

Conclusion: For the first time in the literature, we report an association of Sensenbrenner syndrome with hypothyroidism that resolved after a combined renal and liver transplant. Such findings expand the clinical spectrum of this syndrome. However, a larger cohort is needed to confirm or exclude such an association. Our case highlights the importance of thyroid function monitoring in any patient with renal and liver failure prior to and after a hepatorenal transplant. KEYWORDS: Sensenbrenner syndrome, cranioectodermal dysplasia, WDR35 gene, hypothyroidism, Cranioectodermal dysplasia 2, liver failure, end-stage renal disease.
Source: Hormone Research in Paediatrics - Category: Endocrinology Source Type: research