Robust Neuritogenesis-Promoting Activity by Bis(heptyl)-Cognitin Through the Activation of alpha7-Nicotinic Acetylcholine Receptor/ERK Pathway.

CONCLUSION: B7C promoted neurite outgrowth through the activation of α7-nAChR/ERK pathway, which offers novel insight into the potential application of B7C in the treatment of neurodegenerative disorders.
PMID: 25917415 [PubMed - as supplied by publisher]

Source: CNS Neuroscience and Therapeutics - April 28, 2015 Category: Neuroscience Authors: Hu SQ, Cui W, Mak SH, Choi CL, Hu YJ, Li G, Tsim KW, Pang YP, Han YF Tags: CNS Neurosci Ther Source Type: research