Cancers, Vol. 14, Pages 5917: Ciliary Neurotrophic Factor Modulates Multiple Downstream Signaling Pathways in Prostate Cancer Inhibiting Cell Invasiveness

Conclusions: Our results showed that CNTF and CNTFRa were expressed in PCa and CRPC tissues and that CNTF has a pivotal role in prostate cancer environment remodeling and as a negative modulator of invasion processes of CRPC cell models.

Source: Cancers - November 30, 2022 Category: Cancer & Oncology Authors: Giovanni Tossetta Sonia Fantone Rosaria Gesuita Gaia Goteri Martina Senzacqua Fabio Marcheggiani Luca Tiano Daniela Marzioni Roberta Mazzucchelli Tags: Article Source Type: research