Genomic study of maternal lipid traits in early pregnancy concurs with four known adult lipid loci

Women's blood lipid levels undergo physiological changes during pregnancy compared to pre-pregnancy levels, and the changes are apparent in early gestational weeks1, 2. While these lipid metabolic changes during pregnancy are crucial for fetal development and maintenance of pregnancy, abnormal blood lipid levels during pregnancy are associated with increased risk for adverse pregnancy outcomes3, 4, aberrant fetal growth5-9, and later-life cardiovascular diseases for the mother10, and dyslipidemia and cardiovascular diseases in the offspring during childhood and adulthood11-13.
Source: Journal of Clinical Lipidology - Category: Lipidology Authors: Source Type: research