A novel snake‐venom derived GPIb antagonist, anfibatide, protects mice from acute experimental ischemic stroke and reperfusion injury

CONCLUSIONS AND IMPLICATIONSOur data indicate anfibatide is a safe GPIb antagonist which exerts protective effect on cerebral ischemia and reperfusion injury. Anfibatide, as a promising candidate, could be beneficial for the treatment of ischemic stroke.

Source: British Journal of Pharmacology - April 27, 2015 Category: Drugs & Pharmacology Authors: Ting‐Ting Li, Man‐Li Fan, Shi‐Xiang Hou, Xiao‐Yi Li, Devin M Barry, Hui Jin, Sheng‐Yong Luo, Feng Kong, Lie‐Kui Liu, Xiang‐Rong Dai, Guo‐Hui Zhang, Lan‐Lan Zhou Tags: Research Paper Source Type: research