A multi-centre observational study of HIV, tuberculosis and risk of chronic lung disease in urban West Africa

This study sought to quantify the contribution of HIV and TB infection in addition to conventional CLD risk factors, such as tobacco and biofuel exposure, to CLD in urban West Africa. Design: A multi-centre cross-sectional study was conducted in three community clinics in Lagos, Nigeria between 2018 and 2019. Methods: Spirometry, questionnaires and clinical records were used to estimate prevalence of CLD and association with risk factors. Results: In total, 148 HIV-negative individuals and 170 HIV-positive individuals completed the study. Current cigarette (11 of 318, 3.5%) and lifetime domestic biofuel (6 of 318, 1.8%) exposures were low. Airway obstruction (33 of 170, 19.4% vs. 12 of 148, 8.1%, P = 0.004) and CLD (73 of 170, 42.9% vs. 34 of 148, 23%, P 
Source: AIDS - Category: Infectious Diseases Tags: CLINICAL SCIENCE Source Type: research