Autoantibodies against contactin ‐associated protein‐1 and complexes of paranode‐specific proteins in chronic inflammatory demyelinating polyradiculoneuropathy

ConclusionsThis is the first confirmed Japanese case of anti-Caspr1 antibody-positive CIDP with a clinical signature similar to that of patients of western origins. Our preliminary study did not identify the presence of specific antibodies against the paranode protein complexes, and the primary target antigen is likely Caspr1.

Source: Clinical and Experimental Neuroimmunology - October 27, 2022 Category: Neurology Authors: Michiaki Koga, Toshihiko Maeda, Fumitaka Shimizu, Takashi Kanda Tags: ORIGINAL ARTICLE Source Type: research