Clinicopathological characteristics and genetic variations of uterine tumours resembling ovarian sex cord tumours

Conclusion
UTROSCT is a rare mesenchymal tumour, and biopsy specimens are easily misdiagnosed. UTROSCT diagnosis requires the combined use of biomarkers and molecular detection. BCL-2 has potential diagnostic value as a marker. UTROSCT can have mutations related to the HRR pathway, suggesting that this tumour type may be sensitive to platinum/poly (ADP-ribose) polymerase inhibitors.

Source: Journal of Clinical Pathology - October 18, 2022 Category: Pathology Authors: Ye, S., Wu, J., Yao, L., He, J. Tags: Open access Original research Source Type: research